Lecithin: Cholesterol Acyltransferase of Human Plasma

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Lecithin : Cholesterol Acyltransferase of Human Plasma

The effects of chylomicrons, VLDL (very low density lipoprotein), HDL (high density lipoprotein), and its subfractions HDLz and HDLs, on lecithin: cholesterol acyltransferase reaction in total plasma have been studied. Plasma cholesterol esteritication was measured by the decrease in unesterified cholesterol which was determined by gas-liquid chromatography. Addition of HDL or HDLI had no effec...

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Lecithin : Cholesterol Acyltransferase of Human Plasma

The effects of chylomicrons, VLDL (very low density lipoprotein), HDL (high density lipoprotein), and its subfractions HDLz and HDLs, on lecithin: cholesterol acyltransferase reaction in total plasma have been studied. Plasma cholesterol esteritication was measured by the decrease in unesterified cholesterol which was determined by gas-liquid chromatography. Addition of HDL or HDLI had no effec...

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Lecithin-cholesterol acyltransferase from human plasma.

The effects of chylomicrons, VLDL (very low density lipoprotein), HDL (high density lipoprotein), and its subfractions HDLz and HDLs, on lecithin: cholesterol acyltransferase reaction in total plasma have been studied. Plasma cholesterol esteritication was measured by the decrease in unesterified cholesterol which was determined by gas-liquid chromatography. Addition of HDL or HDLI had no effec...

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Low density lipoprotein-activated lysolecithin acylation by human plasma lecithin-cholesterol acyltransferase. Identity of lysolecithin acyltransferase and lecithin-cholesterol acyltransferase.

There is in normal plasma an enzyme activity which converts labeled lysolecithin to lecithin by an energy-independent low density lipoprotein-activated pathway. Studies were undertaken to compare the identity of this enzyme with lecithin-cholesterol acyltransferase. During purification of the enzyme by ultracentrifugation and by chromatography on high density lipoprotein affinity column, DEAE-S...

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Familial lecithin-cholesterol acyltransferase deficiency.

Familial lecithin-cholesterol acyltransferase deficiency is an uncommon autosomal recessive disorder from a heritable defect in esterification of plasma cholesterol. In 1968, the disease was described by Gjone and Norum in Norway. Our case was a 38-year-old woman. Her disease was manifested by presence of lower extremities edema, proteinuria, corneal opacities, increased plasma cholesterol, and...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1973

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)43222-5